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CaseNex Β· open clinical case reports

The case library every clinician wishes they had at 3 AM.

Peer-reviewed cases from credentialed clinicians. Two ABOPM signatures to publish. Every author credited. Every case hash-chained. Every learner free to read.

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Peer-reviewed quality

Two ABOPM-credentialed faculty sign every case.

Drafts stay drafts until the second signature locks. Dissent is welcome and ledgered. The credential gate is the publication contract β€” not the reading gate.

Every signature carries a bundle SHA-256 + reviewer ORCID. Replay any case's review chain back to the source thread.

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Open access reader

Anyone can read every published case.

No paywall, no journal subscription, no waiting room. Credentialing is for authors, not learners. The bedside clinician at 3 AM and the medical student on rotation see the same case.

Every reader signal mints COIN to the case's author + reviewers. The reader economy funds the writers.

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Author attribution forever

Your name on every case you author, for years.

Authors keep their byline on every reader signal, every CME redemption, every cohort citation. No ghostwriting. No platform that owns your work. Followers can message you directly.

Each case bundle is content-addressed and immutable. Attribution can't be re-written; CANONIC just verifies it.

How peer review works

1

Author in CaseChat

Talk through the case in the chat surface β€” no forms, no markdown, no YAML. The CaseChat assistant builds the mCODE-aligned bundle for you (phenotype, ancestry, ACMG variants, treatment trajectory, outcome).

2

Two-faculty signature

Drafts circulate to two ABOPM-credentialed reviewers. Each signs against the bundle hash; edits are ledgered with diff hunks. Dissent is welcome β€” unresolved disagreement keeps the draft in review, never silently published.

3

Publish + mint

Second signature triggers publish. The bundle lands in R2 (immutable, content-hash addressable). Authors and reviewers earn COIN on every reader utility-signal forever.

Bedside clinician

Search by what's in front of you

Search by phenotype, treatment trajectory, ancestry, or omics signature. Every case carries the reasoning chain that got the diagnosis β€” not just the conclusion. Cite a CaseNex bundle in your tumor-board write-up; the case is hash-pinned so the citation can't drift.

Faculty + reviewer

Author + sign in 15 minutes

Author a case from CaseChat in 15 minutes β€” the assistant assembles the bundle while you talk. Sign a peer's draft and your name lands as reviewer of record. ABOPM CME credit on every signed publish; COIN every time the case is read.

Learner

Real reasoning, real workups

Cases written by the attendings you'd want at your shoulder. Patient privacy preserved (HIPAA-compliant de-identification, no PHI at rest). Real reasoning, real workups, real outcomes β€” not the over-cleaned vignettes that dominate textbook cases.

Why CaseNex isn't a journal

Journals gate readers behind paywalls. CaseNex gates authors behind credentials.

  • Authors must be ABOPM-credentialed. Readers don't need anything.
  • Every case carries the reviewers' signatures. The publication IS the peer review β€” not a step before it.
  • Authors keep attribution forever. No retraction-via-paywall, no journal-owned re-use rights.
  • Reader signals mint COIN to authors + reviewers. The reader economy directly funds the writers.
  • Every claim cites a hash-chained source. Drift is impossible β€” the bundle either resolves or it doesn't.

The 3 AM library

The cases you wish you had on your phone at 3 AM, when the patient in front of you doesn't match anything in the textbook β€” because someone else's patient already did, and they wrote it down.

Published cases

CaseNexPublished CasesMt Sinai Medical Center of Florida

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Who runs this

CaseNex is governed by the American Board of Precision Medicine (ABOPM) credential registry, with peer-signature gates wired to USERS/<NAME>/VITAE.md. Every author's identity is on-chain; every reviewer's credential is provable. The platform is CANONIC; the science is the clinicians.